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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



Dr. Taiwo E. O.*, Akindele R. A., Adefuye B. O., Sofola O. A., Fasanmade A. A., Oyebola D. D. O., Onyemelukwe G. C. and Osonuga I. O.


Objectives: It is uncertain if exercise could influence the occurrence of T2DM in offspring of diabetic parents. Therefore this study was designed to assess the effect of exercise on anthropometric parameters of offspring of T2DM parents compared with offspring of non-diabetic parents. Design: This study involved purposive selection of 50 offspring of T2DM parents attending University Collage Hospital, Ibadan and 50 offspring of non-diabetic parents who are undergraduate students of the University of Ibadan, Nigeria. Participants were randomly assigned into four groups: 25 Normal-weight Offspring of Non-Diabetic Parents (NONDP), 25 Normal-weight Offspring of Diabetic Parents (NODP), 25 Overweight Offspring of Non-Diabetic Parents (OONDP) and 25 Overweight Offspring of Diabetic Parents (OODP). Each participant followed a protocol of graded exercise using tummy trimmer everyday spending 30-45 minutes daily for 24 weeks. Weight and Body Mass Index(BMI) were estimated using standard methods at baseline, six week, 12 week, 18 week and 24 week, respectively. Data were analyzed using descriptive statistic and repeated ANOVA at ? 0.05. Results: Atbaseline, there were reduction in weight (kg) (NONDP:61.47±1.51to59.50±1.60,NODP:67.65±4.77to63.38±5.52,OONDP:66.99±2.01to64.42±1.95andOODP73.28±2.35to71.52±2.35andBMI(kg/m2)(NONDP:21.88±2.78to21.18±2.19,NODP:22.99±1.50to22.26±1.46,OONDP:26.37±4.42 to24.83±4.27 and OODP 29.30±3.23to27.92±3.23 after six months of exercise. Conclusions: Graded exercise alters body weight and BMI in all the groups. The clinical importance of graded exercise in prevention of diabetes mellitus among offspring of diabetic parents looks promising.

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