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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



Harendra Kumar Devarai*, Satyavathi M., G. Ramesh, P. Srinivasa Babu


Bulimia nervosa is the episodic, serious, potentially life-threatening uncontrolled eating disorder characterized by a cycle of binge eating and compensatory behavior such as self-induced vomiting or exercising to excess to avoid gaining weight. This repetitious binge-and-purge cycle can cause damage to your digestive system and create chemical imbalances in the body that harm the functioning of major organs, including the heart. It can even be fata.An individual suffering from bulimia nervosa may reveal several signs and symptoms, many which are the direct result of self-induced vomiting or other forms of purging, especially if the binge/purge cycle is repeated several times a week and/or day. The most dramatic reports of treatment success are of studies using pharmacological therapies, with antidepressant medications being particularly effective. Tricyclic antidepressants, monoamine oxidase inhibitors, and selective serotonin reuptake inhibitors such as fluoxetine, sertraline, and paroxetine have all shown efficacy in the treatment of bulimia nervosa, with responses ranging between reduction of binge eating and/or purging behavior to complete remission of symptoms. As a possible first step, patients should be encouraged to participate in an evidence based self help program. With support and encouragement, some patients with bulimia may find that an evidence based self help program alone produces effective recovery and remission.

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