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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

ANTI-INFLAMMATORY AND ANALGESIC PROPERTIES OF ROSA DAMASCINA MILL - AN INVITRO ANALYSIS

*Dr. Nazargi Mahabob BDS, MDS, Dr. Jayashree Mohan MDS and Dr. Surya Gunasekaran BDS

ABSTRACT

Introduction: Rosa damascena Mill (Rose) is a shrub 1–2 mts in height from the Rosaceae family. Flowers of this plant are large, showy and colorful. Rosa damascena today are highly cultivated all over the world, because it is a popular garden plant and for fragnance. In addition to its perfuming effect, flowers, petals and hips (seed-pot) of Rosa damascena are used for medical purposes. Aims and Objectives: To check these medicinal values of this plant specifically the anti-inflammatory, analgesic and wound healing property this study was undertaken. The aim of this study is to check anti-inflammatory, analgesic and wound healing properties of Rosa Damascena Mill. Materials and Methods: For the application convenience the rose oil converted into two forms one is GEL and other is MOUTH WASH. This was done in JSS College of Pharmacy, Ooty. To check the effects of prepared rose gel and mouthwash it has been tried on 24 Wister rats and 24 Albino mice with the approval of animal ethical committee of JSS College of Pharmacy, Ooty. Results: Animal study confirmed the analgesic, anti-inflammatory and wound healing properties of Rosa damascena mill. To check analgesic property of R.damacena mill two test s were carried out; A.Acetic acid induced Writhing in Mice B. Hot plate method. Both of them proved presence of analgesic activity. Carrageenins induces paw edema test showed the anti-inflammatory property R.Damascena Mill. Conclusion: These two invitro studies proved that the medicinal properties of R.Damascena mill.

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