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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

HISTOPATHOLOGY STUDY TO PROVE THE PROTECTIVE EFFECT OF MAJORANA HORTENSIS AGAINST OXIDATIVE STRESS

Radha Palaniswamy* and Padma Raghunathan

ABSTRACT

Majorana hortensis leaves have been proved to have potential antioxidant activity which was further proved by in vitro studies using precision cut liver slices. Histopathological examinations of the liver slices were used as to examine the hepatic architecture after the exposure of oxidant, namely H2O2. The microscopic lesions produced were usually fatty metamorphosis or centrizonal necroses which were studied. The group which consisted of oxidant and methanolic extract of the leaves showed a protective effect compared to the group which was exposed to the oxidant alone.

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