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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

CRITICAL APPRAISAL OF SHADKRIYAKALA IN CONTEXT OF CARCINOGENESIS

Dr. Umesh Sharma and Dr. Neelima Sharma*

ABSTRACT

Enumerable hypothesis have been put forward with positive evidences regarding the pathogenesis of cancer but still many processes are poorly understood. At present, in the modern oncology the damage of the genetic apparatus of the cell is considered to be the primary cause of cancer, and the pathogenesis of cancer is seen as a process of transformation of a normal cell into a tumor cell, as evidenced by deep fundamental research of the pathogenesis of cancer, which is held exclusively at the cellular, molecular and genetic levels of the organism.[1,2] According to the Ayurvedic concept of pathogenesis of cancer Sushruta has given emphasis on the pathogenesis of a disease under the nomenclature of Shadkriyakala namely; Sanchya, Prakopa, Prasara, Sthansanshrya, Vyakti and Bheda,[3] Modern science believes that the process of carcinogenesis starts nearly 10-15 years earlier than the presentation of disease,[4] which solidifies the concept of Shadkriyakala postulated by Sushruta. The article reviews the principles of shadvidhkriyakaal and great resemblance with modern theories of carcinogenesis.

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