World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , 

World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

COULD THE RELATIONSHIP BETWEEN CRP AND ALBUMIN / GLOBULIN RATIO BE A CLINICAL ACTIVATION INDICATOR IN BEHÇET'S DISEASE?

Dr. Ramazan Ilyas Oner* and Hakan Sezgin Sayiner

ABSTRACT

Aim: The aim of the study was to analyse the relationship between the sedimentation rate and Albumin/Globulin (A/G) ratio along with the CRP level which is considered as an indicator of Behçet’s disease (BD) activation. Method: Fifty patients who were diagnosed with BD were included in this study. CRP levels, sedimentation rate, total protein and albumin levels of patients were retrospectively checked. The patients were classified into two groups: group 1 (0 – 0.8 mg/dl) consisting of those with CRP levels within the normal range and group 2 consisting of those with CRP levels higher than the normal range (CRP> 0.8 mg/dl). Results: There was a statistically significant difference between patients in group 2 and those in group 1 with respect to the sedimentation rate (p = 0.001) and A/G ratio (p = 0.002). Additionally, there was a statistically significant negative correlation between A/G ratio and both CRP levels (r = ? 0.405, p = 0.004) and sedimentation rates (r = ? 0.592, p = 0.000). Conclusion: We believe that in addition to CRP levels, the sedimentation rate and A/G ratio, which are frequently used in clinical evaluation and are easily accessible, may be utilised as indicators of BD disease activity. Therefore, further investigations are needed to clarify the role of these mediators in the BD.

[Full Text Article]

Powered By WJPMR | All Right Reserved

WJPMR