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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

SIGNIFICANCE OF MEAN PLATELET VOLUME, RED CELL DISTRIBUTION WIDTH WITH THE PRESENCE AND SEVERITY OF METABOLIC SYNDROME

Yadav Subhash L., *Dr. Gosavi Satish V., Roy Swetabh, Rode Vikram, Kondeware Mayur

ABSTRACT

Introduction: Metabolic syndrome (MS) is a multiplex risk factor that arises from insulin resistance accompanying abnormal adipose deposition and function. It is a risk factor for coronary heart disease, as well as for diabetes, fatty liver, and several cancers. Recent studies have demonstrated that RDW may also be an effective predictor of morbidity and mortality in various non-communicable diseases. Materials and Methods: The present study was an observational case control study carried out between December 2015 to November 2017 at Tertiary care hospital among patients of Metabolic syndrome is diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III criteria 3 (NCEP ATP 3) attending Medicine outpatient departments. Results: The RDW and MPV values of patients in Group 1 were significantly lesser as compared to RDW and MPV values of patients in Group 2 and Group 3. It was also observed that patients meeting 5 MS criteria (Group 3) had significantly higher MPV and RDW than those meeting 3 MS criteria (Group2). Conclusions: It is known that systemic inflammation is involved in MS and in patient with MS the risk for development CVD increases. The present study is the first report about the association of MPV and RDW with the presence and the severity MS.

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