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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

HOSPITAL BASED STUDY OF CORRELATION BETWEEN MICROALBUMINURIA AND ISCHEMIC STROKE IN WESTERN MAHARASHTRA

Roy Swetabh S., *Kulkarni Sandhya S., Yadav Subhash L., Rode Vikram V., *Kondewar Mayur K.

ABSTRACT

Introduction: Ischemic stroke is defined as the acute onset in neurological deficit following sudden occlusion of blood supply to the brain tissue due to any cause. Microalbuminuria has been associated with clinical risk factors for stroke like diabetes, hypertension, aging, history of myocardial infarction, obesity, smoking and left ventricular hypertrophy and it predicts poor outcome. Materials And Methods: It was an observational Case-Control Study done during Dec 2015 to May 2017 among patients (118 cases and 118 controls) who were admitted with diagnosis of acute ischemic stroke irrespective of age and sex and confirmed by CT scan / MRI brain, within 24 hours after the onset of symptoms in department of General Medicine of a tertiary care hospital. Results: Among the 118 cases, 44 patients had presence of Microalbuminuria (MA positive) and 74 patients had no Microalbuminuria (MA negative), whereas among the 118 controls, only 5 had microalbuminuria and 113 had no microalbuminuria. Patients with acute ischemic stroke are 2.26 times more likely to have microalbuminuria thus depicting significant association between ischemic stroke and microalbuminuria (P value: < 0.0001 & Chi-square value: 39.174). Conclusions: Microalbuminuira as an independent risk factor in acute ischemic stroke has been extensively studied in the western countries, and has successfully established its association with the acute ischemic stroke. This study supports the already prevailing work done to prove the relationship between microalbuminuria and acute ischemic stroke.

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