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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

DIURETIC ACTIVITY OF RUTIN ISOLATED FROM CANSJERA RHEEDII J.GMELIN (OPILIACEAE)

I. Stephen, G. Revathi, Pradeepha P., M. Arthy, Pedapati Renuka Swathi, V. M. Mounnissamy*

ABSTRACT

Rutin isolated from the aerial parts of Cansjera rheedii J.Gmelin (Opiliaceae) has been tested for diuretic activity in rats. The parameters observed for each individual rat included body weight before and after test period, total urine volume (corrected for water intake during the test period), urine concentration of Na+, K+ and Cl—. The values of urine volume and cation excretion were increased with reference to saline control by rutin (100mg per kilogram of body weight). Furesemide was used as a reference diuretic.

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