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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

GIANT CELL FIBROMA AN UNUSUAL LESION OF ORAL CAVITY: A REPORT AND REVIEW OF FOUR CASES

Shruthi K. Patil* and Ahmed Mujib B. R.

ABSTRACT

Background: The giant cell fibroma is a localized reactive proliferation of fibrous tissue, much like the irritation fibroma or fibrous hyperplasia. It usually small, may be sessile or peduncalated. It is painless, often has lobules/ nodules on its surface. It contains cells with large, stellate shaped fibroblasts, near the surface of the fibrous mass, beneath the overlying epithelium Methods: Here we reported four cases between 1991 and 2014 all have distinct clinical features with similar histopathological diagnosis of giant cell fibroma. Results: Four cases have been reported from our department between 1991 and 2014, these case reports revealed different clinical features and provisional diagnosis. Conclusions: All are confirmed histopathologically as giant cell fibroma, it helps in treatment plan and follow up for recurrences. Appropriate histopathological identification is necessary to diagnose the stellate shaped giant bi or multinucleated fibroblasts, which helps in complete surgical excision and follow up of the patient.

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