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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

RETROSPECTIVE PROSPECTIVE OPEN LABEL OBSERVATIONAL STUDY TO EVALUATE THE EFFICACY AND ADVERSE DRUG REACTIONS IN PATIENTS TAKING CONSTAC CHURN FOR LONG TERM IN CONSTIPATION

*Dr. Ashwin Porwal, Dr. Deepak Kulkarni and Dr. Paresh Gandhi

ABSTRACT

Ayurveda practiced in India from thousands of years. Chronic constipation is global issue and more found in old age group. Use of polyherbal formulation in constipation is common and used by >80% population. Long term efficacy and safety concern issues raised in this study by identifying adverse drug reactions. Oral use of constac advised for 180 days to 1200 participants, of which 948 completed the study. Symptoms were analyzed using longos ODS Score system. It was found that use of constac after 120 days giving nearly constant and good results in participants till day 180. Non serious adverse events were also noted and but due to polyherbal origin unable to establish the exact causality with ADRs.

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