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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

SYNTHESIS AND ANTIFUNGAL ACTIVITY OF 1, 3, 4-THIADIAZOLE

Vishal B. Tambe* and Dr. D. H. Nandal

ABSTRACT

Some five membered aromatic systems having three heteroatoms at symmetrical positions such as 1,3,4- thiadiazoles have been studied for their antifungal activity. This research article covers the most active 1,3,4- thiadiazole derivatives that have shown excellent antifungal activity. This research work also discusses the structure-activity relationship of the most potent compounds. It can act as an important tool for medicinal chemists to develop newer compounds possessing 1,3,4-thiadiazole moiety that could be better agents in terms of efficacy and safety.

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