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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



*Dr. Sfaoua H., Allam A., Aarab J., Moukasse Y., Lahlali F. Z., Elmajjaoui S., Kebdani T., Elkacemi H., Benjaafar N.


ABSTRACT Introduction: Carcinosarcoma of the larynx has been occasionally described in the literature, it represents less than 1% of all malignant laryngeal tumors. True carcinosarcoma is defined by mixed malignant epithelial and mesenchymal elements. The diagnosis is difficult due to such variety histopathological features and there is no consensus on the treatment strategy of this rare entity. Case report: In this paper, we report a case of 70 years old male, who presented a persistent hoarseness of voice evolving since six months and was diagnosed by histopathological and immunohistochemical studies to be a case of carcinosarcoma of a left vocal cord, the general physical examination of the patient and workup for extension carried out were normal. He underwent exclusive external beam radiotherapy for 66 Gy in 33 Fractions with 2 Gy per fraction for five days per week, by opposed lateral fields to the larynx. Our patient had an uneventful post–radiation phase, after 3 months, he is asymptomatic and having complete clinial and radiological response. Furthermore, he delivered good results after 12 months of following up. Conclusion: The prognosis of carcinosarcoma of larynx is largely controversial and seems to be poor with high recurrence rate. By contrast, our patient remained in good control after 12 months of following up.

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