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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

EVOLUTION OF ANTI MICROBIAL AND ANTI OXIDANT ACTIVITY OF ALCOHOLIC EXTRACT OF BOUGAINVILLEA GLABRA FLOWERS

Dr. Ch. M. M. Prasada Rao*

ABSTRACT

The aim of the present study was to evaluate the antimicrobial, anti oxidant activity of Bougainvillea glabra leaves extract, plant belongs to family Nyctaginaceae. Antimicrobial activity of alcoholic extracts of these plant leaves were tested against Gram positive and Gram negative bacterial strains by observing the zone of inhibition. Antimicrobial activity was done by disc diffusion method at a concentration of 500 ?g/disc of the extract, using ofloxacin (5?g/disc) as the standard. The bacterial strains used in the study were Staphycococcus aureus, Bacillus subtilis, Escherichia coli, Proteus vulgaris, the anti oxidant activity of extract was tested by using DPPH radical scavenging method at concentration of 5, 10, 15, 20, 25, 30 ?g/ml, using Ascorbic acid as standard. The outcomes of the present study indicated that the alcoholic extract of the Bougainvillea glabra flowers shows the significance anti microbial and anti oxidant activity in a concentration of 500?g/ml and 30 ?g/ml respectively.

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