Abstract

Dr. Malathi Balamurugan*, Dr. Balamurugan Maruthamuthu, Gomathi Ramanathan

ABSTRACT

BACKGROUND: Polycystic Ovary Syndrome (PCOS) is one of the most common endocrinopathy inpremenopausal women. AIM: To analyze the clinical presentation in non-obese women with Polycystic ovarysyndrome (PCOS). METHODOLOGY: The data of the anthropometric measurements, clinical manifestations ofhyperandrogenism, menstrual history and life style were collected from 24 young non-obese (selected according toBMI) patients with polycystic ovary syndrome and compared with 30 regularly menstruating age matched BMImatched normal women. Unpaired Student t test for continuous variables and chi square test for categoricalvariables, Pearsons correlation and Binary logistic regression analysis was done to bring out the associationbetween the variables. RESULTS: Among the hyperandrogenic features the incidence of Hirsutism (defined as aFerriman-Gallwey score > or = 6) was 62.5%, fourth highest prevailing androgenic sign, next only to dandruff(91.76%), Acne (75%) and androgenic alopesia (66.66%). Menstrual history: 66.66% had Oligomenorrhea, 62.5%,Chronic pelvic pain, 54.16% Premenstrual tension 25% History of similar problems in family 25%, along withsignificantly altered life style parameters. Waist circumference, W / H ratio, Age of Menarche (years), Hirsutismscore were significantly correlated with p value of <0.001, 0.01,< 0.001,< 0.001 with non-obese PCOS. Of thehyperandrogenic parameters, Acanthosis nigricans , Hidradenitis Suppurtivaand Androgenic alopecia came out assignificant individual predictors of a person to have PCOS who is of ideal and lean weight with p value< 0.05,<0.001, severe hyperandrogenism, altered lifestyle, disturbed menstruation and related factors than controls, which mayhave severed health implications later in life.