REVIEW ON: RACENT APPROACH TO COLON AS TARGATED DRUG DELIVERY SYSTEN IN FUTURE
*Dr. Rashmi Kumari, Dr. Vachaspati Dubey, Dr. S. K. Mishra and Ruchi Singh
ABSTRACT
Colon is targated for colon associated disease Like Chron’s disease, Inflammatory bowel disease, Colon cancer, Ulcerative colitis and also for the delivery site for systemic delivery of drugs like antihypertensive, Antihistaminic. Colon target is more specific those drug which is inactive at upper part of GIT. To achive maximum site specific when two or more approaches are prefferd on single approaches like Time dependent, Osmotic controlled, Prodrug approach, pH controlled system are very effective. Major goal for colon as targated system to achive effective concentration of drug release in systemic circulation and hence increase bioavailability.
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