World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

EVALUATION OF ANTI HYPERLIPIDEMIC ACTIVITY IN RODENTS USING LEAF EXTRACTS OF CITHAREXYLUMSERRATUM

Mandapalli Sireesha* M. Jalaiah, D. Dhachinamoorthi

ABSTRACT

The hypolipidemic effect of various extracts of citharexylumserratumwas investigated in rats suffering from high cholesterol, diet induced hyperlipidemia and the phytochemicals in the extracts were analyzed. The high-cholesterol diet caused a significant increase in total lipids, total cholesterol (TC), total triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and the atherogenic index, whereas the level of high-density lipoprotein cholesterol (HDL-C) was significantly decreased. The animals were divided into 6 groups where 2 used as test, 1 for standard, 1 for control, 1 for diet induced hyperlipidemic and 1 for the activity of physical exercise. The groups with anti hyperlipidemic medication and without medication by exposing to physical exercise are compared in one aspect and however the group treated with methanolic extract showed better activity than standard and other groups.

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