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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



Anupam Shukla, Dr. Dheeraj Raj*, Pradeep Kumar and Sanjeev Kumar


Introduction: Esophageal cancer is the eighth most common cancer worldwide and the sixth most common cause of death from cancer.[1,2,3] Its high mortality rate makes it a major concern. Probably no other cancer causes greater misery to the patient due to development of an inability to swallow even fluids. The disease is specially common in countries of the so called "Asian esophageal cancer belt" including India. A detailed study of this disease and its management in SVBP Hospital Meerut has been attempted by our study. It also provides an elaborate review of current literature pertaining to the disease and concludes by comparing the results of the present study with the published data in the international scenario. Aims: Objective is to study the demographic and clinical profile of the patients of Esophageal cancer in western Uttar Pradesh. Methods: The study was conducted in SVBP Hospital Meerut between June 2016 to October 2017.Total of 46 patients with diagnosis of Carcinoma esophagus were admitted in department of surgery during this period and were analysed prospectively. The data regarding demographic and clinical profile were obtained by questionnaire-interview with the patients and their relatives. Follow up period was one and half year. The data was analysed by SPSSS 21.0 version. Results: Out of 46 patients 52% (N=24) were in age group 51-60 years. Male female ratio was 2.5:1. Most of the patients (80%) belongs to low socio-economic status level. About 57% of the patients in our study were non vegetarians, most of them consumed food which was hot and spicy. Alcohol and smoking was found to be independent risk factor for carcinoma esophagus and in our study. Majority of the patients 60.8% (N=28) present with complaint of dysphagia to both solid and liquid food. Apart from dysphagia, loss of weight and appetite, odynophagia, regurgitation, chest pain, hoarsness of voice and dyspnoea were other symptoms commonly present in our patients. Upper GI endoscopy and biopsy of lesion followed by CECT thorax and upper abdomen was the main investigation tool performed in our patients for confirmation of diagnosis and locoregional extent of the disease. Out of 46 patients only 18 patients were found to be candidate for esophagectomy.

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