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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

PREPARATION AND EVALUATION OF TELMISARTAN SUSTAINED RELEASE TABLETS BY USING EUDRAGIT POLYMER

Inturi Ramya*, Dr. M. Dhanalakshmi and D. Ramchakradhar

ABSTRACT

The aim of the present study was to develop Telmisartan Sustained release tablets to maintain constant therapeutic levels of the drug for over 24 hrs. Eudragit RSPO, Eudragit RLPO were used as polymers. All the formulations were passed various physicochemical evaluation parameters such as bulk density, tapped density, carrs index, hausners ratio, angle of repose, weight variation, hardness, thickness, friability and drug content. From the dissolution studies it was evident that the formulation F10 showed better and desired drug release pattern i.e., 98.96 % in 12 hours. It contains the Eudragit RLPO as polymer. It followed Peppas release kinetics mechanism.

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