World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , IFSIJ Measure of Journal Quality , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

Abstract

IN SILICO STUDIES ON DENGUE AND CHIKUNGUNYA VIRAL PROTEINS WITH SELECTED EMBLICA OFFICINALIS (AMLA) LEAVES CONSTITUENTS

Pavithra K., Nisha R., Rameen Taj S., Shethal V. Rao, Tulasi D. P., *Dr. Balasubramanian Sathyamurthy

ABSTRACT

Dengue and chikungunya virus contains seven proteins, which are considered to be the most effective for drug designing. Recent studies have shown that these proteins can effectively cause the inactivation of dengue and chikungunya disease in humans. Phytochemicals present in Emblica offiinalis are found to have anti-bacterial and anti-cancer properties. In our study, the binding efficiency of 4 compounds that is present in the Emblica officinalis with all the fourteen proteins was performed through Insilico methods. By our virtual screening and molecular docking result, we found that the Benzoic acid, 3,4,5-trihydroxy- have highest binding affinity with the proteins and we also predicted the binding site amino acid residues and the type of hydrogen bonding.

[Full Text Article]    [Download Certificate]

Powered By WJPMR | All Right Reserved

WJPMR