Abstract

Mohit Sharma*, Mahesh Patel, Vinod Dhakad, Nayan Gupta, Abhinav Deshpande and Ruchit Kansaria

ABSTRACT

Malignant mesothelioma is usually a fatal neoplasm for which operation has been the main stay of treatment because chemotherapy and radiotherapy are relatively ineffective. The choice of operation for malignant mesothelioma remains controversial. Reducing the bulk of tumor with cytoreductive surgery is key to extending survival. Two surgeries have been developed, extrapleural pneumonectomy(EPP) and pleurectomy. Extrapleural pneumonectomy has been advocated because it allows complete removal of gross tumor and can be associated with long term survival. Extrapleural pneumonectomy is associated good local control of disease with greater likelyhood of relapse in distant sites. We report a new case of diffuse malignant mesothelioma involving left lung without any distant metastasis. Patient had no history of asbestos exposure. Patient underwent extrapleural pneumonectomy with excision of left hemidiaphragm. A complete en-block resection was performed. Final histopathology and immunohistochemistry confirmed the diagnosis as malignant epithelial mesothelioma.