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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

ASSESSMENT OF RING ENHANCING LESIONS OF BRAIN USING MAGNETIC RESONANCE IMAGING AND MAGNETIC RESONANCE SPECTROSCOPY

Dr. Sheikh Shahnawaz, Dr. Iqubal Hussain Dar*, Dr Asif Majid Wani and Dr. Vineet Wadhwa

ABSTRACT

Background: Most common lesions found in brain on neuroimaging are ring-enhancing lesions. These can be caused by a variety of infectious, neoplastic, inflammatory or vascular diseases. Distinguishing imaging characteristics of non-neoplastic causes from neoplastic lesions is extremely important because a misdiagnosis can lead to unwarranted neurosurgery and exposure to toxic chemotherapy or potentially harmful brain irradiation. Advanced diagnostic techniques, such as Magnetic resonance imaging, diffusion-weighted magnetic resonance imaging (MRI), magnetic resonance spectroscopy, may help in establishing the etiology. The basic intention of this study is to describe the characteristic Magnetic resonance imaging findings in various ring enhancing lesions which will help in their characterization. Objectives: To study the characteristic MR imaging and MR spectroscopic findings of various ring enhancing lesions and their differential diagnosis on MRI brain. Methods: 40 patients (males=22; females=18) were evaluated in this study conducted at Govt medical college (GMC SRINAGAR), from JULY to DEC 2018 over a period of 6 months. MRI along with MRS was performed using 3T siemens Magnetom skyra in patients ranging from ages of 10-70 years. Results: 40 patients were evaluated out of those 18 cases were tuberculomas, 10 abcesses,, 6 metastasis, 4 cases of primary brain tumor 1 case of NCC and 1case of demyelinating lesions. Seizures are the commonest presenting complaint seen in 25 cases. Interpretation & Conclusion: On the basis of this study we conclude that Magnetic resonance imaging coupled with Magnetic resonance spectroscopy provides the fairly accurate diagnosis in differentiating various ring enhancing lesions of brain and helps to narrow the long list of differential diagnosis of ring enhancing lesions in brain.

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