World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , IFSIJ Measure of Journal Quality , 

World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.639

ICV : 78.6

Abstract

EFFECT OF BED REST AND NIFEDIPINE ON INHIBITING PRETERM LABOUR

Dr. Amna Khalid*, Dr. Muhammad Amir Mushtaq and Dr. Muhammad Adnan Bilal

ABSTRACT

Objective: To compare the success rate of nifedipine administration as a tocolytic agent and bed rest for preventing uterine contraction of pregnant women with threatened preterm labour. Methods: A total of 188 pregnant women with threatened preterm labour between 26-35 weeks were enrolled in this study. Cervical measurement was performed in all patients. All women in each group (94 cases) were randomly inhibited uterine contraction with nifedipine administration and bed rest intervention. Results: Nifedipine took the shorter time than bed rest for contraction inhibition in threatened preterm labour with statistical significance. (nifedipine: 2.31 ± 1.19 hours, bed rest: 2.54 ± 0.71 hours) From subgroup analysis, the success rate of nifedipine inhibition and bed rest in the patients with cervical length <3 cm were 83.9% (26 cases) and 55.2% (16 cases), respectively, which was different with statistical significance. Conclusions: Nifedipine can be used successfully to inhibit contractions in threatened preterm labour. However, if the cervical length was ? 3 cm, bed rest should be firstly applied to avoid unnecessary medical intervention.

[Full Text Article]

Powered By WJPMR | All Right Reserved

WJPMR