Abstract

T. Ramya Krishna*, U. Swathi, S. Priyanka, Anugna K., S. Bala Bhavani, M. Suvarn

ABSTRACT

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. A number of physical, chemical or biological agents are known to mutate and activate these proto-oncogenes into active and cancer causing oncogenes. Chemotherapy (chemo) usually refers to the use of medicines or drugs to treat cancer. Chemo can work throughout the whole body. This means chemo can kill cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour. ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs. The side effects of chemotherapy can be unpleasant, but they must be measured against the treatment's ability to destroy cancer. ADRs mostly occurred in the age group of 41-50 years and some of the studies have found the most common age group to be between 50 and 70 years. The most common ADRs found to be were nausea and vomiting. However, ADRs of cancer chemotherapy is common, that can lead to disability and even death. Their prompt recognition, adequate and effective clinical management is mandatory in promoting patients safety.