Abstract

Dhevahi Elumalei*, Jainamboo Meera Balamurugan Santhalingam, Arvind Srinivas, Janaranjhani, Praseetha Ramakrishnan, Subramanian M. N. and Sumathi Gnanadesikan

ABSTRACT

Urinary tract infection (UTI) second largest disease, with developing antibiotic resistant strains in uropathogens, pulls attention and concern in medical treatment over the past years. The most common uropathogens found is Escherichia coli (E. coli), commonly treated by fluroquinolones for UTI infections.[1] Aim: Our study aimed at evaluating the antimicrobial patterns of common uropathogen Escherichia coli towards the frequently prescribed fluroquinolones for uncomplicated UTI in our tertiary care hospital at Mangadu South India, during Aug 2014 and July 2016. Study Subjects & Results: A total of 4217 urine samples analysed, common uropathogen was identified as E.Coli. (53%) from uncomplicated UTI patients. Antimicrobial susceptibility performed for E. Coli towards the five common fluroquinolones, shows susceptibility as 62.4 % Gatifloxacin, 73.6% Levofloxacin 70.4% Ofloxacin 55.6% Norfloxacin, and only 39 % Ciproflox, were effective for treatment of UTI. High resistance was noticed towards Ciprofloxacin, Norfloxacin and the overall resistance toward the commonly used fuoroquinolones is between 25-30% which needs early attention. Conclusion: Study was able to analyse the fluroquinolone pattern of antibiotic treatment within the uncomplicated UTI patients group in our hospital.