World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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Abstract

A COMPARATIVE CLINICAL STUDY ON MITRAPANCHAKA YOGA AND AVALGUJABEEJADI LEPA IN THE MANAGEMENT OF SHWITRA W.S.R. TO VITILIGO

Dr. Nirank Kumar*, Dr. A. R. Dave and Dr. Monika Katiyar

ABSTRACT

Shwitra is a disease described in Ayurveda; which is produced by vitiation of Vata, Pitta and Kapha Doshas. The signs and symptoms of Shwitra are; non exudative white, red or coppery-red coloured patches on the skin, destruction of the skin lusture, loss and discolouration of the hair, roughness, dryness, itching and burning sensation of the patches. It can be correlated with Vitiligo which is progressive whitening of the skin and hair characterized by the total absence of melanocytes in affected areas of the skin. Aim: To assess and compare the clinical efficacy of Mitrapanchaka Yoga with and without Avalgujbeejadi lepa in the management of Shwitra (Vitiligo).Material and methods: In this trial, 34 patients were registered, out of which 30 completed the treatment. Patients were randomly divided in two groups with the help of computer generated random selection method viz. Group A and Group B. In Group A classical Mridu Samshodhana was given followed by oral administration of Mitrapanchaka Yoga as a Shamana Yoga, followed by Avalgujbeejadi lepa for local application. In Group B patients were treated with Mridu Samshodhana followed by oral administration of Mitrapanchaka Yoga internally. Special scoring pattern was adopted for scrutinizing the symptomatology. The score was given on the basis of Size, Colour, Number of patches, percentage of body area involvement and chronicity of patches. VASI Score to know overall effect of therapy on two groups and VIS-22 Score for each patient was calculated Results:On Applying VASI Score both groups showed highly significant results.VIS-22 Score was suggestive of high psychological involvement in disease. Conclusion: On comparison group A showed better results in percentage changes, result difference was significant in improvement in number of patches in Group A, which suggests that Mitrapanchaka Yoga and Avalgujabeejadi Lepa together give better results than Mitrapanchaka Yoga alone.

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