World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

ANTI-OXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF DELONIX ELATA (FLOWERS)

Prof. A. Rajeshkanna*, Dr. M. M. Senthamilselvi, D. Prabhakaran, S. Solomon and N. Muruganantham

ABSTRACT

Delonix elata L. (Ceasalpinaceae family), is extensively used by the traditional medical practitioners of Karnataka, India, to cure jaundice, bronchial and rheumatic diseases. The present study was to screen the in vitro antioxidant and anti-inflammatory behaviors of the sample isolated from the ethyl acetate fraction of flowers of Delonix elata. Anti-inflammatory activity of the sample was determined by HRBC membrane stabilization and Albumin denaturation methods. Anti-oxidant activity of the sample was determined by DPPH assay and ABTS method. In vitro antioxidant and anti-inflammatory activity revealed that the sample isolated from the ethyl acetate fraction showed more potent anti-oxidant and anti-inflammatory activities. Further studies will be needed in future in order to determine which one or more of its active constituents have the major antioxidant and anti-inflammatory effects.

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