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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.103

ICV : 56.51

Abstract

CLINICAL EVALUATION OF EFFICACY OF ‘MANSYADI GHAN VATI’ AND ‘TAKRA-AMALAKI SHIRODHARA’ IN THE MANAGEMENT OF HYPERTENSION

Dr. Rahul Kumar Sanwariya* and Dr. Pramod Kumar Mishra

ABSTRACT

Hypertension (Persistent high blood pressure) is not a single disease, it is a syndrome of various etiologies, multiple pathogen city, and wide range of clinical manifestations and if remains untreated will leads to several fatal complications. It is a major risk factor for the development of cardiovascular disease and cerebrovascular disease causing high rate of mortality and morbidity. Keeping in view the increasing incidence of this problem a study was conducted with following Aims and Objectives- To study the etiopathogenesis of Hypertension in Ayurvedic context. To study the efficacy of “Mansyadi ghan vati” in management of Hypertension. To study the efficacy of “Mansyadi ghan vati” along with “Takra-amalaki shirodhara” in the management of Hypertension. Material and Methods- The study was conducted on 40 clinically diagnosed patient of Hypertension and randomly divided into two groups. In group-A: 20 well diagnosed patients of Hypertension will be administered with Mansyadi ghan vati 2 tab twice a day with lukewarm water for 45days. (Each tablet of 500 mg.). In group-B: 20 well diagnosed patients of Hypertension will be administered with Mansyadi ghan vati 2 tab twice for 45 days along with Takra-amalaki shirodhara for 14 days. Statistical Analysis-was done with help of Instate Graph Pad software3.1 using Wilcoxon matched-pairs signed ranks test and Mann-Whitney test. Results- Statistically highly significant result was observed in both Groups. Conclusion- Therapy in the form of administration of Mansyadi ghan vati and Takra-Amlaki Shirodhara separately or in combination is a safe and effective in the management of Uccharaktachapa (Essential Hypertension).

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