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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.103

ICV : 56.51

Abstract

DYSCHROMATOSIS UNIVERSALIS HEREDITERIA

Dr. Astuty Apurwa (MBBS), Dr. Nandita Patel (MBBS)*, Dr. Nitin Nadkarni (MD DVD) and Dr. Sharmila Patil (MD DDV)

ABSTRACT

Dyschromatosis universalis hereditaria is a rare autosomal dominant genodermatosis seen most commonly in Japan. It may sometimes be inherited as autosomal recessive pattern, predominant in females. The spectrum of the diseases includes dyschromatosis universalis hereditaria (DUH), dyschromatosis symmetrica hereditaria (DSH/acropigmentation of Dohi) and a segmental form called as unilateral dermatomal pigmentary dermatosis (systemic involvement). It is often characterized by hypo- and hyperpigmented asymptomatic macules, distributed symmetrically on the extremities.Histological findings are thinning of epidermis with increased basal pigmentation and few macrosomes. Papillary dermis showed somewhat coarse collagen and perivascular lymphomonocytic infilterate. Hereby, we report a rare case of DUH in male with autosomal recessive inheritance pattern and no systemic complains.

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