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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.103

ICV : 56.51

Abstract

THE INTEREST OF MUCOLYTIC DRUGS IN BRONCHIAL AIRWAY CLEARANCE IN LITTLE CHILDS

F. Z. Aglili, M. A. Radouani, A. Barkat* and A. El Hassani

ABSTRACT

Introduction The tracheobronchial obstruction is often associated with various respiratory diseases. Chest physiotherapy is the most effective way to treat bronchial congestion while the usefulness of mucolytic drugs remains controversial. The aim of this study is to compare the effectiveness of single chest physiotherapy and respiratory physiotherapy associated with mucolytic drugs in bronchiolar pathology of infants and small childs. Materials and methods this prospective study was conducted during the period between October 2016 and Mars 2017. 100 patients aged 6 months to 3 years were recruited. We compared 2 groups; one group receiving in addition to the chest physiotherapy mucolytic drugs, the second group followed only physiotherapy treatment. Results The study shows that mucolytic treatment has no impact on the easiness of airway clearance by chest physiotherapy; and neither the appearance, the abundance or thixotropy are modified and mucoregulators would not help with evacuation at bronchial decluttering but it’s a way of adaptation to the to the effort of chest physiotherapy session. Conclusion However, mucolytics prescription has no impact on the easiness of airway clearance but can be useful to facilitate the adaptation of the infant and small child illness and stress.

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