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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.103

ICV : 56.51

Abstract

ASSOCIATION BETWEEN GLYCOSYLATED HEMOGLOBIN AND MICRO-ALBUMINURIA IN PATIENTS WITH TYPE II DIABETES MELLITUS

Dr. Moumita Dam and Dr. P. Karkuzhali

ABSTRACT

Diabetes is the most common metabolic disorder around the world. It is characterised by varying degree of insulin resistance, impaired insulin secretion and increased glucose production. Diabetic nephropathy is the commonest cause of morbidity and premature mortality in patients with Insulin dependent diabetes mellitus (IDDM).[1-2] Microalbuminuria (increased urinary albumin excretion) is the earliest sign, which can progress to overt albuminuria if left untreated, and then ultimately lead to renal failure.[3] Improved glycemic control tend to delay the onset of microalbuminuria, but the development of cost-effective preventive strategies requires knowledge of the increase in the risk of nephropathy associated with increase in the degree of hyperglycemia.[4-6] The current study was conducted to investigate the correlation of microalbuminuria with levels of HbA1c. This correlation can have imply on deciding how strictly the blood sugar levels of diabetic patients need to be controlled for optimum health and prevention of complications like diabetic nephropathy for indicating risk of Diabetic Nephropathy in poorly controlled diabetic patients.

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