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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 4.103

ICV : 78.6

Abstract

DISCOID LUPUS ERYTHEMATOSUS – A REPORT OF TWO CASES

Dr. Y. Shreya*, Dr. Tirumala Kanakadurga Sripati, Dr. P. Karkuzhali, Dr. Hemalatha Ganapathy

ABSTRACT

Lupus Erythematosus is a chronic, multi-system, auto-immune disease. It manifests with diverse signs and symptoms; with localized cutaneous LE (CLE) on one end of the spectrum and severe systemic LE (SLE) on the other end. Cutaneous lupus is categorized as: Chronic Cutaneous Lupus (CCLE), Sub-acute Cutaneous Lupus (SCLE) and Acute Cutaneous Lupus (ACLE). Discoid Lupus Erythematosus (DLE) is the most common of the CCLEs. Most patients with untreated classic DLE lesions suffer indolent progression, resulting in large areas of cutaneous dystrophy and scarring alopecia, which can be psychosocially devastating. Progression to systemic lupus erythematosus (SLE) is a possibility, necessitating early diagnosis and prompt treatment with regular follow-up.

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