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World Journal of Pharmaceutical
and Medical Research

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301

ICV : 78.6



Dr. Deepika Gupta*, Dr. Rajesh Agrahari, Dr. Kamal Sachdev and Dr. Richa Garg


In Ayurvedic literature 20 types of Prameha are described which are in general characterized by production of excess amount of urine (Prabhootmutrata / polyuria) and increased frequency of micturation Baram-baram mehati. Any of the prameha when left untreated is converted into Madhumeha and patient passes large amount of sweet urine as madhu (glucosuria). According to above features Madhumeha is correlated with Diabetes Mellitus in allied sciences. Type II Diabetes Mellitus is a metabolic disorder characterized by persistent hyperglycemia due to less production of insulin and increased resistance of insulin receptors (due to avaran of insulin receptors by meda dhatu. The persistent hyperglycemia, hyperlipidemia and hypercholesterolemia Bahu-abadha meda in long term causes non-enzymatic glycosylation of vascular endothelium and also causes development of atherosclerosis in vessels which helps in development of different complications of diabetes mellitus, such as- Microvascular Complications which includes Retinopathy, Neuropathy, Nephropathy and Macrovascular Complications which includes Coronary Artery Disease, Decreased Cerebral Circulation, Peripheral Vascular Disease (s/a- Diabetic Foot). The best way to prevent Diabetes Mellitus is Nidanaparivarjana, Pathyapathya palana and Sadvrita Palana. If Diabetes Mellitus has already developed then its complications should be prevented by using Madhumeha-har dravyas to control blood sugar level, hyperlipidemia, hypercholesterolemia and complications related with kidney, eyes, nerves, etc. Once complication develops they should be treated by above measures and by using specific treatment s/a- Netra Kriyakalpa for retinopathy, Prachalan, Sodhan and Ropan Karrna and Prameh Pidika Nasak Chikitsa for Prameha Pidika and diabetic foot ulcer etc. Control of associated problems s/a- hypertension is also important.

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