World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

CORRELATION OF PORTAL VEIN DIAMETER, SPLENOMEGALY AND THROMBOCYTOPENIA WITH GASTRO-ESPOHAGEAL VARICES IN CIRRHOTIC PATIENTS

Dr. Inderpal Singh*, Dr. Rishabh Sehgal, Dr. Harsimranjit Singh and Dr. Puneet Chuchra

ABSTRACT

Background: Portal hypertension is one of the complication of chronic liver disease due to cirrhosis liver. Portal vein diameter, Splenomegaly and Thrombocytopenia can be used as Non- Invasive markers for the presence of Gastro-esophageal Varices in cirrhotic patients. Early detection of Gastro-Esophageal Varices can prevent the UGI Variceal bleed in cirrhotic patients. In this article it is established that the correlation of portal vein diameter, splenomegaly and thrombocytopenia with Gastro-Esophageal Varices helps in early detection of gastro-esophageal Varices. Method: Our study was conducted on 100 patients of cirrhosis and investigations for platelet count, Ultrasonography for Portal vein Diameter and Upper GI endoscopy for Esophageal varices detection. Results: Our Study demonstrated that thrombocytopenia, presence of portal hypertension with splenomegaly and portal vein diameter are strong predictors of developing gastro-esophageal varices in cirrhotic patients. Conclusion: In cirrhotic patients Gastro-esophageal varices has direct correlation with Portal hypertension and inverse correlation with platelet count.

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