Abstract

Ajit Khapne*, Trupti Dumore, Dr. Ritesh Bathe and Shubham Shende

ABSTRACT

The main aim and objectives of this research was to formulate a tablet from the combination of Carica Papaya and Murraya Koenigii aqueous and hydroalcoholic leaves extract tablets with different concentrations (10%, 20%, 30%, and 40) of Microcrystalline cellulose (MCC) as a binder using the direct compression method. The experimental methods and evaluation of the tablet?s physical properties (i.e., weight variation, friability, hardness, disintegration time, dissolution time, and physical appearance) was done using standard methods of extracts i.e. alkaloids and flavonoids was determined by the spectrophotometry method and Thin Layer Chromatography (TLC). The results of The tablet was light brown and had both flat top and bottom, a specific odor and a bitter taste. The physical properties of the tablet were in accordance with pharmaceutical standards. The Conclusions of this study has been concluded that MCC concentration can be used as a binder to formulate Carica Papaya leaves extracts and Murraya Koenigii leaves extract tablet into high-quality and ready-to-consume tablets and hydroalcoholic extract is more suitable for consume as compare to aqueous extract tablet.