Abstract

Salla Surya Prakasarao*, Salla Sweta Ramani, Suma Pusapati, Srikanth Gummadi, Kartheek Pyla

ABSTRACT

Background: Postoperative Atrial fibrillation (POAF) is the most frequent arrhythmia observed after Coronary artery bypass grafting (CABG). Worldwide incidence is documented to be 20-30% in patients undergoing isolated Coronary artery bypass grafting (CABG). There is no published data for Indian population so far. Hence, the objective of our study is to analyse the occurrence of new-onset POAF in our Indian population and to assess whether the preoperative beta-blocker therapy has any role in its prevention. Material and Methods: This is a retrospective and prospective observational study of coronary artery disease patients in NRI Institute of medical scineces, Visakhapatnam, who underwent coronary artery bypass grafting at various institutions between January 2017 and December 2017. The patients with documented AF during the preoperative period and patients undergoing associated cardiac procedures have been excluded from the study. Data has been collected from the patients’ medical records and the relative clinical variables were analysed. Chi-square test used for statistical analysis. Results: 113 patients with coronary artery disease (followed up at our centre) were found to have undergone CABG during the study period. Among the 113 patients, 95 (84.07%) were males and 18 (16%) were females. The mean age of patients developing AF was 61.9±8.7 and for patients in sinus rhythm was 58.7±7.9 years (range: 37-80 years). 79 patients received preoperative Carvedilol and 34 patients were free from Carvedilol usage. The overall incidence of AF was 6.16%. 3.1% of patients with Carvedilol were noted to have AF while 13.23% of patients with no Carvedilol coverage developed new-onset AF (p