World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

ACUTE RENAL FAILURE AFTER USING DEXKETOPROFEN: 3 CASE REPORTS

Dr. Ali Gurel* and Bilge Aygen

ABSTRACT

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used all over the world. Acute renal failure (ARF) is a known complication of NSAIDs. Especially in cases of hypovolemia NSAIDs inhibit the enzyme cyclo-oxygenase that regulate the synthesis of prostaglandins from arachidonic acid and it may result vasoconstriction and reversible renal failure. Dexketoprofen is enantiomer of ketoprofen and is a nonspecific NSAID in aryl-proprionic acid group. In this article we present 3 patients with acute renal failure and with history of the use of dexketoprofen.

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