Abstract

Enas H. Hameed*, Sura Z. Hussein, Nazar A. N. Abed

ABSTRACT

Tumor markers are substances produced by the tumors or by other cells of the body in response to cancer or certain benign conditions. The cancer antigen (CA15-3) and carcinoembryonic antigen (CEA) are tumor markers that are often expressed in people with breast cancer. These tumor markers are most useful for monitoring response to therapy and detecting early relapse. Serum samples were collected from 140 women were ,50 of these women were control and 90 women were breast cancer patients attending to cancer center in Erbil city from Jaunary 2017 to Augest 2017.Study populations classified into three groups which age ranged from (29-65) years, total subjects, pre and postmenopausal women. The results of CEA and CA15-3were showed a highly significant increase (P?0.01) in total and (pre and postmenopausal) breast cancer patients compare with healthy control. Elevated CA15-3 levels are more common in metastatic breast cancer patients than with other tumor markers (e.g., CEA) and concluded from this study CEA and CA15-3 levels were increased, in patients compare to healthy control group.