NON OBESE YOUNG INDIAN WOMEN MENSTRUAL IRREGULARITIES HAVE NORMAL QT AND CORRECTED QT PARAMETERS – A CASE CONTROL STUDY
Dr. Malathi Balamurugan* and Dr. Balamurugan Maruthamuthu
ABSTRACT
Background: Menstrual irregularities (MI) is a wide spectrum of clinical disorders with prevalence of 2%- 17% in India. The QTc interval duration, which is related to cardiac arrhythmia, sudden death and a sign of cardiac autonomic neuropathy, has not been investigated thoroughly in these patients. Aim: To investigate the potential alterations in electrocardiographic – QT parameters in lean and ideal weight young Indian patients with MI Methodology: 19 patients with MI who were lean or ideal weight as per WHO criteria and 25 BMI matched normally menstruating women served as study participants. All of them underwent assessments clinically and by appropriate laboratory tests. Using Bazetts formula QT interval, minimum and maximum QT interval (QT Max and QT Min), QT dispersion (QTd), QT interval corrected for heart rate (QTc), minimum and maximum QT interval (QTcmin and QTcmax, respectively) rate, corrected QT dispersion (QTcd). Unpaired Student t test was used, Pearsons correlation and Binary logistic regression analysis was done to bring out the association between the variables. Results: QT (0.378 ± .027 vs 0.429 ± .053, P value < 0.001) ; QTmax max (0.419 ± .035 vs 0.464 ± 0.064, P value
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