VARIATION IN THE CLINICO-PATHOLOGIC BEHAVIOR OF ORAL CROHNS DISEASE: A CASE REPORT
*Dr. Cheshta Walia, Dr. Rudra Prasad Chatterjee, Dr. Sudip Roy, SK. Abdul Mahmud
ABSTRACT
Crohns disease is poorly understood inflammatory bowel disease. It is characterized by accumulation of noncaseating granuloma formed as an inflammatory response to intestinal microbes. Clinical features include mucosal ulceration or erythemas associated with abdominal pain and diarrhea that often follow periods of relapse and remission. It occurs usually in 3rd to 5th decade of life with 60% individual presents early manifestation in oral cavity. The exact etiology is unclear but studies suggest that inflammatory pathway plays an intricate role in maintaining high levels of cytokine IFN-? in disease progression. The author aims to highlight the case of oral crohns disease which has preceded before the emergence of gastrointestinal features in an adult patient.
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