IN SILICO STUDIES ON DENGUE AND RHINO VIRAL STRUCTURAL PROTEINS WITH SELECTED CORIANDRUM SATIVUM L LEAVES CONSTITUENTS
Mahesh K., Nagarjun N., Aniruddha B.S., Ashwini B.M., Murugan Rajadurai and *Balasubramanian Sathyamurthy
ABSTRACT
Dengue virus contains two structural proteins. Rhino virus contains four structural proteins. These are considered to be the most effective for drug designing. Phytochemicals present in Coriandrum sativum L. Functions as aromatizing agents and has relaxant activity in the alimentary tract. They are found to have antibacterial and anticanacerous properties.In this study, the binding efficiency of 4 compounds that are present in the Coriandrum sativum L.with all the selected structural proteins were performed through Insilico methods. Our molecular docking result, we found that Dodecanal has the highest binding affinity with the selected dengue and Rhino structural proteins.
[Full Text Article] [Download Certificate]