Abstract

Dr. Muhammad Shahzeb Khan Khakwani*, Dr. Muhammad Umair and Dr. Fahad Sardar

ABSTRACT

Background: Diabetes Mellitus is a disease which produces multi-system complications. Heart failure is the end result of cardiovascular complications due to presence of diabetic cardiomyopathy, indicated by diastolic left ventricular dysfunction, which can be easily diagnosed with echocardiography. The objective of this study Frequency of diastolic dysfunction in cases of Diabetes Mellitus. Methods: In this descriptive case series, 150 consecutive patients with diabetes mellitus having normal blood pressure and normal resting electrocardiogram and without any symptoms of heart failure were selected. Duration of the study was 6 month from July 2017 to December 2017 at Nishtar Hospital Multan. 150 cases of diabetes mellitus of both gender i.e. male/female with age more than 40 years and duration of DM of at least 2 years and of type II DM were included. The cases with previous history of valvular disease, acute coronary syndrome, liver or renal disease were excluded from the study. Presence or absence of diastolic dysfunction was noted in each case. Results: Of the total, 63 (42%) of patients had diastolic dysfunction with male predominance. Conclusion: We observed Diastolic dysfunction is seen in nearly half of the patients with type 2 diabetes mellitus. We observed that there is no specific time or duration of diabetes after which diastolic dysfunction will occur. It can encounter even younger in younger patients and those having shorter duration of disease. Diastolic dysfunction can be used as an early indicator, as it is a precursor to increased Left Ventricular hypertrophy and clinical left ventricular dysfunction.