World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

MICROBIAL FLORA AND ITS ANTIBIOTICS SENSITIVITY IN DIABETIC ODONTOGENIC CELLULITIS---A CASE SERIES

Dr. Neha Usman, *Dr. Asif Nazir Ch. Dr. Muhammad Imran Saleh, Dr. Rana Majid Mansoor, Dr. Muhammad Mustafa, Malik Muhammad Ali and Professor Dr. Muhammad Usman Akhtar

ABSTRACT

Background: Facial spaces are potential planes in head and neck region between the fasciae and underlying organs or tissues. Infections involving these spaces may give varying signs and symptoms depending upon the area involved and sometimes potentially fatal if not managed promptly and adequately. The infections of odontogenic origin are mostly notorious for their spread to these potential spaces. The diabetic patients have shown special concerns as being aggressive in nature. Objective: To find out the types of microorganisms involved in odontogenic space infections in diabetic patients and their antibiotic sensitivity patterns. Methodology: A total of 300 diabetic patients with odontogenic cellulitis were selected for study in Oral and Maxillofacial Surgery Units of de’Montmorency College of Dentistry/ Punjab Dental Hospital Lahore and Nishtar Institute of Dentistry Multan from February 2017 to January 2019. A structured proforma was used to record patient’s demographic data, type of tooth/teeth and fascial space involved in odontogenic infection and clinical and radiographic presentation of infected maxillofacial region. After ethical committee approval and consent of patients, the surgical decompression/drainage was performed mostly under local anesthesia and culture and sensitivity specimens were obtained for laboratory testing. Results: The mean age of patients was 44.50±14.38 years with male to female ratio of 1.16:1. The most common bacteria involved in odontogenic space infections in diabetic patients were staphylococci (31.3%) and the most sensitive antibiotic in diabetic odontogenic infections was levofloxacin (57.6%). Conclusion: The study shall be helpful to the clinicians in diabetic odontogenic infections management using levofloxacin with promising results.

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