ANALISIS OF URINARY MICRO ALBUMIN AND Α1MICROGLOBULIN IN EARLY DETECTION OF DIABETIC NEPHROPATHY
*Dr. Muhammad Munzir, Dr. Munaum Ali Khan and Dr. Muhammad Muneeb
ABSTRACT
Objective: To analyze the values of combined detection of urinary micro albumin (mAlb), ?1?microglobulin (?1-MG) and N-acetyl-?-D-glucosaminidase (NAG) in the early diagnosis of diabetic nephropathy (DN). Methods: Ninety-four patients with early DN who were admitted to the Sheikh Zayed Hospital, Rahim Yar Khan between April 2016 and April 2017 were selected and set as a DN group. Moreover, seventy-six patients with diabetes who were admitted to the hospital in the same period were selected and set as a diabetes group, and sixty-four healthy people were selected as set as a control group. The urinary mAlb, ?1-MG and NAG of the three groups were detected. Moreover, the patients were divided into a favorable blood glucose control group and a poor blood glucose control group according to the blood glucose control condition of the patients. The detection results of the three groups were compared and statistically analyzed. Results: The urinary mAlb, ?1-MG and NAG levels of the DN group were significantly higher than those of the diabetes group and control group, and the differences had statistical significance (P
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