World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

OSTEOPOROSIS IN CASES OF PEPTIC ULCER DISEASE

Dr. Zunaira Khalid, Dr. Sheza Aslam and Dr. Muhammad Hamza Khawaja*

ABSTRACT

Background: Osteoporosis among peptic ulcer disease is one of the complications usually reported. Objective: To determine the frequency of osteoporosis in patients with peptic ulcer disease. Methodology: It was a descriptive, cross sectional study that was conducted at Medical Department Lahore General Hospital, Lahore from 1st January to 30thAugust 2018. In this study the cases of age 18 years or more diagnosed with peptic ulcer disease on history and then confirmed on upper GI endoscopy, were included. These cases were then assessed on DEXA scan and osteoporosis was labelled as yes where there was score of less than 2.5. Data was entered and analyzed by using SPSS version 19. Results: In this study there were total 60 cases out of which 28 were males and 32 females. The mean age was 43.23±8.13 years. The mean duration of PUD was 3.2±0.31 years and mean T score was 1.2±0.8. Osteoporosis was seen in 4 (6.67%) of cases. Osteoporosis was more seen in females affecting 03 (9.38%) cases of their respective groups (p= 0.02). There was no significant difference in terms of duration of PUD with osteoporosis (p= 0.86). Conclusion: Osteoporosis is recently studied complication of peptic ulcer disease and is not very common, but still present among many cases of peptic ulcer disease as shown by this study.

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