Abstract

*Mansa Devi and Asokan Vasudevan

ABSTRACT

Introduction: Vomiting in pregnancy is the first and foremost symptom of pregnancy. Emesis Gravidarum is a worldwide common obstetrical problem seen in the first trimester of pregnancy in about 50-60% of pregnant women. Ayurvedic classics have mentioned Garbhini Chardi as one among the Vyakta Garbha Lakshanas, which can be correlated with Emesis Gravidarum. The present study drug Subidhabala khand is used for the management of Garbhini chardi. Methodology: This single arm clinical trial study was conducted among 30 pregnant women pre and post test design at PIA, PU, Vadodara. The drugs of Subidhabala khand were collected in the form of raw material and the Subidhabala khand (granules) was prepared at GMP certified pharmacy of PIA, Vadodara. Drug Standardization and authentication was done before the clinical trial. These patients were selected based on the criteria of inclusion, exclusion and assessment were done as per the standard parameters. 30 patients were given Subidhabala khanda orally in a dose of 6 gm twice a day before food with Ksheera as Anupana. The response to the treatment was recorded and therapeutic effects were evaluated by symptomatic relief and based on assessment criteria. Aim: To evaluate the therapeutic efficacy of Subidhabala khand in Garbhini Chhardi. Objective: To observe the add on benefits of Subidhabala Khand in relieving the symptomatology of Garbhini Chardi and its effect on fetal and maternal well being. Result: In the present study, Subidhabala khanda was having good effect in reducing Chardi vegas-44.56%, Hrullas-37.37%, Aruchi-36.07%, Quantity of Vomitus-47.72% and in Content of vomitus-47.72% relief was found and adverse effects were observed during the study period. Conclusion: Total thirty two patients were enrolled in study. Two patients dropped out of the study, but all remaining thirty patients experienced improvement at the end of treatment. In the study significant improvement (P