COST AND OUTCOMES OF DIRECT ACTING ANTIVIRAL THERAPY IN CHRONIC HEPATITIS C PATIENTS WITH GENOTYPE 3
Anum Hanif, Bazgha Ashfaq, Bushra Ali Sherazi, Dr. Tahir Anwer, Jawad Ashfaq
ABSTRACT
Context: Hepatitis is derived from Ancient Greek words hepa which means liver and itis which means inflammation. Hepatitis viruses have 5 different types each associated with a different etiology, distribution, mode of transmission and mortality risks. However, the virus of interest here being hepatitis C virus, which transmitted via blood. Aims and Objectives: The objectives of this study are to evaluate the prescription drugs cost of current treatment regimens available for HCV Genotype 3. Design, setting and participants: An observational and cross-sectional study was carried out in the community involving patients with diagnosed Hepatitis C. Data collection, analysis, and interpretation were stretch to a span of 6 months from August 2016 – January 2017. Main outcome Measure: Gender, age, monthly income, awareness and knowledge about HCV, knowledge about cause of HCV, knowledge about medication of HCV, blood profile in last three months, blood profile in last six months. Results: Most of the population in Pakistan belongs from the middle class 55% of the population for this sample size was belonging from middle class while 30% were very poor only 13% from upper middle class. Conclusion: In this, study the assessment of the treatment outcomes for different regimens of Direct Acting Antivirals (DAAs) in terms of patient compliance, relapse rate, improvement in liver architecture, the disability-free period the patient gets using a certain combination of drugs. The entire research directed to figure out the best treatment option for curing genotype 3 infection.
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