Abstract

Dr. Anber Rahim*, Dr. Khadija Hussain, Dr. Tooba Inam

ABSTRACT

Introduction: Gestational Diabetes is defined as onset of glucose intolerance at varying degree or first diagnosed during pregnancy. GDM has a potential risk to the mother as well as the fetus. Obesity has been designated as one of the most important global health threats worldwide, and its prevalence has been increasing among women of reproductive age. Objectives of the study: The main objective of the study is to analyze the gestational weight gain among women with gestational diabetes mellitus in local population of Pakistan. Material and methods: This cross sectional study was conducted at Nishtar hospital, Multan during March 2018 to November 2018. The data was collected from 293 female patients according to the ethical committee of hospital. We designed a study to associate maternal BMI and GWG with pregnancy outcomes in local women of Pakistan with GDM. Demographic profile (name, age, contact no.) was taken. History of related risk factors Physical Examination and investigation included obstetric ultrasound and blood samples were obtained from each subject to know about their clinical parameters like Fasting blood sugar level, random blood sugar level for Screening and diagnosis, HBA1C, Glucose tolerance test of patients was above the normal range. Results: According to the pre-pregnancy BMI, 96 women (11.5%) were underweight, 558 (67.1%) were of normal weight, 134 (16.1%) were overweight and 44 (5.3%) were obese (Table 1). The level of glycosylated hemoglobin was significantly higher in the overweight and obese groups than in normal weight and underweight groups (P < 0.05). In addition, birth weight was significantly higher in overweight or obese women than in underweight women (P < 0.05). There were no significant differences between the four pre-pregnancy BMI categories in maternal age, parity, height and gestational weeks. Conclusion: It is reasoned that high pre-pregnancy BMI and unnecessary GWG are related with higher frequencies of LGA, and in addition other unfavorable results in Pakistani ladies with GDM.