SPIRONOLACTONE INDUCED GYNECOMASTIA- A CASE REPORT
Palanisamy Sharmila Nirojini*, Maddirevula Maneesh Kumar Reddy, Rama Rao Nadendla4 and A. Pramila Rani
ABSTRACT
Gynecomastia is proliferation male breast tissue due to an imbalance in estrogen and androgen action. Though it is rare it causes anxiety, embarrassment and physical discomfort in the affected male. This case report is of a 69-year-old male patient who presented with the symptom of painful swelling in his both breasts. He is suffering from hypothyroidism, type 1 diabetes mellitus and myocardial infarction from past few years and using Eltroxin, Atorvastatin, Aspirin, Clopidogrel, Glimipride and Metformin. He was also diagnosed with clinically controlled Congestive Cardiac Failure (CCF) for which he was prescribed Lasilactone (Furosemide 20mg and Spironolactone 50mg) and developed enlargement of his breast after 9 months of treatment and diagnosed by the physician as bilateral gynecomastia. The physician withdrawn Lasilactone and added Furosemide 40mg. but the poor prognosis of his pedal edema caused by his CCF made the patient to take Lasilactone and the symptoms of gynecomastia recurred again. Diagnosing drug induced gynecomastia and discontinuing the drug causing it will prevent the need of surgery for gynecomastia.
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