World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

FIBROIDS AND FERTILITY: A LITERATURE REVIEW

*M. Sebti, M. C. Fourati, F. Zidane, P. R. M. Yousfi and P. R S. Bargach

ABSTRACT

Leiomyoma, more commonly known as uterine myoma or fibroma, is a benign tumor of the human uterus that grows at the expense of smooth muscle cells. These tumors consist of smooth muscle fibers with elongated nuclei, surrounded by collagen fibers and a pseudocapsule formed by smooth muscle cells, and are poorly vascularized. Myomas are extremely variable in form, each characterized by their size, consistency and position relative to the myometrium, and are mostly multiple within the same uterus. Fibroids are classified ultrasonographically into different types based on the position of their largest transverse diameter according to the FIGO classification. Fibroids are the most common uterine tumors in women of childbearing age and are present in 20% to 50% of these women, and their controversial relationship to infertility remains a matter of debate. The management of a woman with a fibroid and a desire for pregnancy is discussed. It is reported that 5% to 10% of infertility cases prior to medical management are associated with the presence of uterine fibroids. Uterine fibroids are considered to be the sole infertility factor in only 1-3% of cases.

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